Melatonin Supplementation in Children: A Narrative Review of Indications, Safety, and Potential Long-Term Effects
Heather Hydzik, ND
Labrix LLC, 16255 SE 130th Ave, Clackamas, OR 97015, USA


Exogenous melatonin in children
Pediatric melatonin use
Childhood insomnia


Insomnia and sleep disturbance are common in children and adolescents. Parents and medical providers often wonder whether melatonin supplementation is a safe choice in these age groups. Small-scale studies suggest that long-term melatonin supplementation safely and effectively treats sleep onset insomnia in children with attention-deficit hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD). Documented side effects have been minimal and relatively benign. This paper is a brief review of the clinical indications, side effects, and potential long-term implications of supplementing melatonin in children.



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